Further to DrugAlert Vol 500, HPS Pharmacies wish to advise that Juno Pharmaceuticals has issued a medical safety alert for metaraminol syringes as follows:
Metaraminol Juno Syringe
Metaraminol (as tartrate) 5mg/10mL
Juno Pharmaceuticals has been made aware of leakage concerns relating to Metaraminol Juno 5mg/10mL pre-filled syringes when used with certain brands or types of IV extension sets.
Following local studies to determine IV set compatibility, Juno advises that the following needle-free connectors are compatible with the pre-filled syringes without the need for additional adaptors:
- ICU Medical – Nanoclave IV bungs;
- ICU Medical – Microclave Clear Connector;
- ICU Medical – Neutron;
- Carefusion™ SmartSite valve®; and
- BMDi TUTA Healthcare – Pulse needle-free injection site.
If narrow-bore tubing is to be used, it is recommended that a compatible Luer lock needle-free connector is connected to the extension set prior to connection of the syringe. Metaraminol Juno pre-filled syringes have been designed for manual bolus dosing. Alternative presentations (i.e. ampoules) should be used for IV infusions.
Juno Pharmaceuticals will continue to identify additional IV connectors that are compatible with these syringes. If you use a connector not listed above, Juno asks that you contact them so they can perform the relevant studies to determine compatibility.
Retain this notice in a prominent position, including in other related business units for one month. Report any problems identified with medicines, vaccines or medical devices to the TGA.