Availability of Prostin® E2

Further to DrugAlert vol 1040, HPS Pharmacies wish to provide an update on the availability of Prostin^® E2 as follows:

Prostin^® E2 Vaginal Gel
Dinoprostone 1mg
ARTG 9983

Prostin^® E2 Vaginal Gel
Dinoprostone 2mg
ARTG 9984

Normal supplies of the 1mg product are expected to resume by the end of October 2026, with the 2mg product following at the end of November 2026.

An internationally registered alternative of each strength has been approved for supply under Section 19A of the Therapeutic Goods Act 1989. Unfortunately, these products are also unavailable due to a manufacturer-level supply failure in the UK. The S19A permit holder is unable to give an estimated return date for these products.

No equivalent products are currently available. Potential alternatives that prescribers may consider include dinoprostone controlled-release pessary (Cervidil^®), oxytocin, and misoprostol. Availability of these products may vary throughout the country.

Retain this notice in a prominent position, including in other related business units until supplies return to normal. Report any problems identified with medicines, vaccines or medical devices to the TGA.

Should you require further information regarding this matter, please contact Pfizer on 1800 675 229, or your pharmacist at HPS Pharmacies.

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