Safety Alert


Further to DrugAlert Volumes 219, DrugAlert Volume 221, and DrugAlert Volume 224, HPS Pharmacies wish to provide an update on the ongoing supply issues of:

Suxamethonium Chloride Injection BP
100mg in 2mL, 50 x 2mL
ARTG ID 11988

Despite advice that normal supply had resumed in April, AstraZeneca have been unable to maintain stock levels and the use of alternative products has continued.

One of these, Succinolin® (suxamethonii hydrochloridum anhydricum) Injection 100mg/2mL is distributed under Section 19(A) of the Therapeutic Goods Act, which permits supply of an unregistered product, in situations where there is an interruption to supply of a registered product for which there is a recognised medical need.

HPS Pharmacies wish to alert prescribers to an insert that is distributed with this product that advises caution regarding dose substitution due to it being manufactured from a different salt form of suxamethonium. Succinolin® (suxamethonii hydrochloridum anhydricum) Injection 100mg/2mL delivers 10% more suxamethonium than the Australian registered product, Suxamethonium Chloride Injection BP 100mg in 2mL.

Furthermore, HPS Pharmacies are also pleased to advise that Suxamethonium Chloride Injection BP 100mg in 2mL is again available, although remaining supplies of any alternative products may be fully used before returning to regular stocks.

Report any problems identified with medicines, vaccines or medical devices to the TGA.

Should you require further information regarding this matter, please contact your pharmacist at HPS Pharmacies, Medsurge Healthcare on 1300 788 261, or AstraZeneca Customer Service on 1800 226 591.

Information regarding expected dates for supply may vary subject to delays which are out of our control. HPS Pharmacies does not accept responsibility for such changes but will endeavour to keep our clients updated as information is made available from drug manufacturers or wholesalers.

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