Drug Availability Update

Further to DrugAlert Volume 392, HPS Pharmacies wish to give notice that Aspen Pharmacare Australia Pty Ltd is continuing to experience a supply interruption for the following local anaesthetic products:

Product

ARTG

Current Status

Marcain 0.25% 5 x 20mL

48380

Out of stock

Marcain 0.5% 5 x 10mL

11937

Stock shortage anticipated

Marcain 0.5% 5 x 20mL

48328

Out of stock

Marcain with Adrenaline 1:200,000 5 x 20mL

48329

Out of stock

Naropin 0.2% 5 x 10mL

52406

Available

Naropin 0.2% 5 x 20mL

52405

Available

Naropin 0.75% 5 x 10mL

52400

Out of stock

Naropin 0.75% 5 x 20mL

52399

Available

Naropin 1% 5 x 10mL

52398

Available

Naropin 1% 5 x 20mL

52397

Available

Xylocaine® 1% 5 x 20mL

48361

Out of stock

Xylocaine® 2% 5 x 20mL

48364

Out of stock

 

This supply interruption is due to a fire at the manufacturing site. While the manufacturer is taking action to resolve this issue, normal supplies of sterile theatre packed Marcain 0.5% 5 x 20mL and Xylocaine 1% 5 x 20mL are not expected to resume until late in the third quarter of 2018. Supplies of Marcain with adrenaline 1:200,000 5 x 20mL are expected to be available from 1st July 2018. Availability of the other sterile theatre packed products has not been confirmed by Aspen at this stage. No other Marcain with adrenaline or Xylocaine with adrenaline products are currently affected by this supply interruption.

Aspen advises that the following substitutions could be considered during this supply interruption:

  • Marcain 0.25% 5 x 20mL – one 10mL Marcain 0.5% non-sterile theatre packed polyamp can be diluted with 10mL saline to obtain 20mL Marcain 0.25%
  • Marcain 0.5% 5 x 10mL – one 10mL Marcain 0.5% non-sterile theatre packed polyamp can be considered as an indirect substitute
  • Marcain 0.5% 5 x 20mL – two 10mL Marcain 0.5% non-sterile theatre packed polyamps can be considered as an indirect substitute
  • Xylocaine 1% 5 x 20mL – four 5mL Xylocaine 1% 50 x 5mL polyamps (non-sterile theatre packed) can be considered as an indirect substitute
  • Xylocaine 2% 5 x 20mL – four 5mL Xylocaine 2% 50 x 5mL polyamps (non-sterile theatre packed) can be considered as an indirect substitute

The product information should be consulted for further information on the appropriate use of these agents. In order to avoid medication errors, it is also requested that all staff exercise additional diligence when prescribing, supplying, and administering these products during this supply interruption.

Retain this notice in a prominent position, including in other related business units until supplies return to normal. Report any problems identified with medicines, vaccines or medical devices to the TGA.

Should you require further information regarding this matter, please contact your pharmacist at HPS Pharmacies, or Aspen Pharmacare Australia on 1300 659 646.

Information regarding expected dates for supply may vary subject to delays which are out of our control. HPS Pharmacies does not accept responsibility for such changes but will endeavour to keep our clients updated as information is made available from drug manufacturers or wholesalers.

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